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management hematology neurology algorithm chronic cll criticalcare differentiation emergencies foamed gravis hemeonc hyponatremia leukemia lymphocytic mds myelitis myelodysplasia myelodysplastic oncologic
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
loss of smile 3. ... life-threatening Differential ... Diagnosis - ... /Edrophonium test ... #Gravis #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... #APML #diagnosis ... management #hematology #oncology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Then, ask 3 questions ... to work through ... demyelination syndrome ... #Diagnosis #Treatment ... #management #nephrology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... after ~48 h) 3. ... 48 h, duration 3– ... #HemeOnc #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Agranulocytosis 3. ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... Infectious: Leprosy 3. ... Postsynaptic: Myasthenia ... dystrophies Work ... #Diagnosis #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology ... #oncology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- More than 2/3 ... negative, MOG-IgG test ... Transverse Myelitis Treatment ... #management #neurology ... #differential
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
between these 3 ... which all carry treatment ... hormones that work ... for Refeeding Syndrome ... #diagnosis #differential
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