15 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... + MRI lesions + ... Infectious: ... #Brain #differential ... #diagnosis #causes
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... parietal - Size lesions ... Enhancement: multifocal lesions ... punched-out" cystic lesions ... Infections in HIV
Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic
 Most common cause ... Differential diagnosis ... Multiple Sclerosis: CNS ... hyperreflexia, multiple lesions ... hyperreflexia, spinal cord lesion
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
nervous system (CNS ... pachymeningitis • HIV ... neuropathy (LHON) plus MRI ... lesions and clinical ... noninflammatory #differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
pulmonary etc) • CNS ... Space occupying lesions ... Brain tumor • Lesions ... Lesions Of The Peripheral ... EMG) studies • MRI
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
cells in the CNS ... bilateral white matter lesions ... well-defined than PML lesions ... The clinical syndrome ... disorder #dementia #AIDS
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... compressive cord lesion ... less swollen - Lesion ... or optic nerve lesions ... simplex virus, HIV
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
osteitis, cutaneous lesions ... pneumonia, skin lesions ... Leprae - Cutaneous lesions ... flare, ocular lesions ... Worsening of cutaneous lesions
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... Polymorphic skin lesions ... Multiple skin lesions ... Lymphadenopathy, CNS ... #HIV #AIDS #pulmonary
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
ring-enhanced lesion ... Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... ring-enhancement lesion ... neurological symptoms • Caused