7 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV dementia ... Pathophysiology ... integrity of the blood-brain ... penetrance through the blood-brain ... motor slowing and ataxia
Causes of Myoclonus - Differential Diagnosis
LOCALIZATION:
 • Cortical: Focal/multifocal: Distal UL+ Face, Action/sensitive induced
 • Sub-Cortical:
Causes of Myoclonus ... degenerations, dementias ... acid-base, opioids, psychiatric ... MarcoMalaga97 #Myoclonus ... Differential #Diagnosis #Causes
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... increase venous blood ... Ophthalmoplegia - Ataxia ... vascular contraction, blood ... beriberi #nutrition #pathophysiology
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
ingestion and most cases ... extremities), myoclonus ... Serotonin #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
acids elevated blood ... hormone levels cause ... Complications #pathophysiology ... signs #symptoms #psychiatry