39 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs / Symptoms ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
hemorrhagic rash; symptoms ... disseminates in blood ... fetal blood vessel ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fits, Hemiplegia, Ataxia ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
10,000 ft) • Symptoms ... • Symptoms: Hypoxemic ... • Signs/Symptoms ... • Signs/Symptoms ... • Pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... workup for specific symptoms ... for secondary causes ... eosinophilia (common causes ... organ-specific signs or symptoms
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... plateletcount), peripheral blood ... pylori test (GI symptoms ... Differential #Diagnosis #Causes ... #Workup #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... transfusion • Pathophysiology
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
the formation of blood ... clots in small blood ... Symptoms of VITT ... The exact cause ... thrombocytopenia #COVID #pathophysiology
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
autosomal recessive blood ... go on to block blood ... Crises can be precipitated ... The underlying pathophysiology ... Features #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology