5794 results
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
#Differential diagnosis ... of myopathy # ... #Hypothyroid myopathy ... Statin-induced myopathy ... Cocaine-induced myopathy
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... Statin-induced myopathy ... - Necrotizing myopathy ... Atorvastatin Diagnosis ... #diagnosis #management
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... MuscleWeakness #Myopathy ... #mimics #diagnosis
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
rimmed vacuoles HIV myopathy ... load Drug-induced myopathy ... Gemcitabine Lupus Myopathy ... 5-15% of lupus myopathy ... #differential #diagnosis
Neurological Patterns of Weakness
 • Hemispheric lesion
 • Brainstem lesion
 • Spinal cord lesion
 • Polyneuropathy
Polyneuropathy • Myopathy ... Patterns #Weakness #diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... /full triad at diagnosis ... and anti-HMGCR myopathy ... Autoimmune #Myositis #diagnosis
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Critical Illness Myopathy ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy ... #differential #diagnosis
Abdominal Distention - Differential Diagnostic Algorithm
Ascites
Bowel Dilatation
Other Causes
Mechanical Obstruction
 • Adhesions 60%
 • Volvulus 3%
 •
- Differential Diagnostic ... • Ischemic Myopathic ... Scleroderma • Familial Myopathy ... #Differential #Diagnosis
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
- Differential Diagnosis ... , Inflammatory Myopathy ... #Differential #Diagnosis
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
MSK: Proximal myopathy ... Symptoms #Signs #Diagnosis