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diagnosis differential rheumatology clinical neurology signs symptoms causes systemic pocus algorithm lupus management physicalexam erythematosus msk sle syndrome ultrasound video
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... Inclusion body myositis ... #Hypothyroid myopathy ... Statin-induced myopathy ... Cocaine-induced myopathy
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Inclusion Body Myositis ... , +Anti-dsDNA, Myositis ... BostonChiefs #Myositis ... #Myopathies #myopathy
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Inclusion Body Myositis ... Myopathies #Idiopathic #Myopathy
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Mediated Necrotizing Myopathy ... Inclusion Body Myositis ... MithuRheum #Myositis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... Necrotizing myopathy ... triad of ILD, myositis ... and anti-HMGCR myopathy ... #Autoimmune #Myositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... • Inflammatory myopathy ... inclusion body myositis ... Statin-induced myopathy ... - Necrotizing myopathy
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
• Overlap Myositis ... Any inflammatory myopathy ... Inclusion body myositis ... Inflammatory myopathy ... #dermatology #Myopathy
Important Causes of Diplopia TIER 1-CRITICAL Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn TIER 2-EMERGENT: Vertebral dissection, Myasthenia gravis,
sclerosis, Thyroid myopathy ... neuropathy, Orbital myositis
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Critical Illness Myopathy ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy ... Inclusion body myositis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
proximal weakness Myopathy ... mediated necrotizing myopathy ... Inclusion body myositis ... anti-RNP - (Myositis ... inclusion body myositis
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