1489 results
Pancreatitis Complications - Necrotizing Pancreatitis and Fluid Collections
Interstitial Edematous (85%):
 • Acute Pancreatic Fluid Collection (APFC)
15%): • Acute necrotic ... • Walled-off necrosis ... pancreatic duct syndrome
Management of Necrotizing Pancreatitis

Severe Pancreatitis
Pathophysiology
Diagnosis of Pancreatic Necrosis
Infected Necrosis
Complications of Severe Pancreatitis: 
1) Pancreatic Fistula
2) Disconnected
of Pancreatic Necrosis ... Infected Necrosis ... Pancreatic Duct Syndrome ... Guidelines #Pancreatic #Necrosis
Calcific Uremic Arteriolopathy (calciphylaxis) - Hand photo and XRay
Based on this image, what is the likely
calciphylaxis) - clinical syndrome ... calcification -> tissue necrosis ... Note necrotic lesions
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Esophageal Necrosis ... direct injury with necrosis ... Necrosis should ... resolution of necrosis ... #Esophageal #Necrosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
cholestasis, no necrosis ... HELLP Syndrome ... unless massive necrosis ... Patchy/extensive necrosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
a.k.a. cardiorenal syndrome ... a.k.a. hepatorenal syndrome ... Acute tubular necrosis
Compartment Syndrome Pearls
A vicious cycle of increased pressure within a facial compartment leading to compression of
Compartment Syndrome ... hypoxia → Ischemia → Necrosis ... Swelling 2° to necrosis ... Myoglobinuria & Tubular necrosis ... #Compartment #Syndrome
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
acute tubular necrosis ... tuberculosis Fatty - Nephrotic ... syndrome ("Maltese
Complications of Acute Pancreatitis
Systemic
 - Systemic inflammatory response syndrome (SIRS)
 - Hypoxia
 - Hyperglycaemia
 - Hypocalcaemia
inflammatory response syndrome ... Pancreatic - Necrosis
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... Full-thickness epidermal necrosis ... SCVMCMed #DRESS #Syndrome