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diagnosis differential causes management rheumatology sodium activation anemia aplastic gout hypotonic macrophage mas neurology oncology physiologic rhabdomyolysis seizures table
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Syndrome of Inappropriate ... Neurologic trauma • Drugs ... • Reduced GFR, AKI ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Syndrome of Inappropriate ... Neurologic trauma • Drugs ... • Reduced GFR, AKI ... #Nephrology #Differential
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Algorithm Hypertonic ... Cirrhosis, Nephrotic syndrome ... > 30): SIADH, Medications ... Primary polydipsia, Low ... #sodium #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia), Low ... table #sodium #nephrology
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
vasoconstriction syndrome ... Toxic: Alcohol, Medication ... , Recreational drugs ... Hyperglycemia, Hyponatremia ... #Causes #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Toxins - Drugs ... declines > ALT) • AKI ... Hyperuricemia • Hyponatremia ... + myoglobin AKI ... #nephrology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
inflammatory disease How ... ) • Sepsis • Drug-induced ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Cytotoxic drugs ... - Antithyroid medications ... aplastic anemia Treatment ... may result from low ... Anemia #oncology #hematology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... • Medications ... comorbidities/drug ... gout • Oral drug ... #rheumatology
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