10 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... loss (Diarrhea) Renal ... Loop and thiazide diuretics ... Bartter syndrome, Gitelman ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... blood flow • ... activities • Diuretic ... syndrome #Mechanisms #pathophysiology ... #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... mOsm/kg - Implies renal ... • Euvolemic (Low ... #Algorithm #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Chloridorrhea Renal ... • Penicillins Renal ... tubular transport • Diuretics ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap #Nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... Alkalosis: Emesis, Diuretics ... Bartter syndrome, Gitelman ... differential #potassium #nephrology ... #low
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Decreased Intake: • Low ... LOSS: - Diuresis ... - Bartter - Gitelman ... #Pathophysiology ... #Nephrology #Chloride
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... alkalosis • Normal or low ... • Hypokalemia (renal ... Syndrome #diagnosis #nephrology ... #management #pathophysiology