15 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... loop of Henle Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... loss (Diarrhea) Renal ... Loop and thiazide diuretics ... , Gitelman syndrom ... potassium #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... • Increased renal ... activities • Diuretic ... #Mechanisms #pathophysiology ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... mOsm/kg - Implies renal ... , Cushing syndrome ... #Algorithm #nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Normotensive - No diuretic ... dr_missyhanna #Gitelman ... #Syndrome #Diagnosis ... #Workup #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... volume loss - diuretics ... • nephrotic syndrome ... Hypernatremia #Diagnosis #Workup ... #Algorithm #Nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... hypokalemia • Renal ... Post-hypercapnia • Diuretics ... , Gitelman's syndrome ... #causes #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
after renal tubule ... generally indicates a renal ... furosemide-like lesion) • Gitelman ... thiazide-sensitive site ... Diagnosis #Causes #nephrology