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diagnosis differential hematology oncology treatment causes classification dermatology lung mds myelodysplastic pulmonary vasculitis abg acid acidbase aids amiodarone aplastic arteritis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... hemoglobinuria (PNH ... Extravascular #Causes ... #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... #rheumatology #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #treatment #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... #oncology #hematology ... #diagnosis #management
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
are much more common ... Concussion Other Causes ... are much more common ... retinopathy (sickle cell anemia ... ophthalmology #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Most common cytopenia ... Out Secondary Causes ... #diagnosis #hematology
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
L L-lactate (common ... D-lactate (short bowel syndrome ... Renal failure (uremia ... Acetazolamide Causes ... - Salicylates Causes
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... by case) • Surgery ... #Treatment #management ... #pharmacology #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
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