248 results
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... perfusion to meet O2 ... Distributive Shock ... Hypovolemic Shock ... differential #diagnosis #algorithm
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
demand, decreased O2 ... SVR and altered O2 ... therefore inadequate O2 ... therefore inadequate O2 ... therefore inadequate O2
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
demand, decreased O2 ... SVR and altered O2 ... therefore inadequate O2 ... therefore inadequate O2 ... therefore inadequate O2
Causes of Generalized Hypoxia - Differential Diagnosis
 • Hypoxemic - Not enough O2 (Most Common)
 •
Hypoxemic - Not enough O2 ... faulty carrier • Shock ... Cells can't use O2
Shock - Differential Diagnosis Algorithm
Warm Extremities
 - Distributive Shock - Low JVP
Shock - Differential ... Diagnosis Algorithm ... - Distributive Shock ... Sounds • Pulmonary ... Differential #Diagnosis #Algorithm
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Differential Diagnosis Algorithm ... Erythropoietin, O2 ... Cyanosis without Pulmonary ... Apnea • Chronic Pulmonary ... Differential #Diagnosis #Algorithm
Hypotension / Shock Differential Diagnosis Algorithm
Hypovolemic:
 • Poor oral intake
 • Hemorrhage
 • Renal loss
 •
Hypotension / Shock ... Differential Diagnosis Algorithm ... valvulopathy • Pulmonary ... obstruction • Pulmonary ... Differential #Diagnosis #Algorithm
Hypoxemia vs Hypoxia
Hypoxemia - Partial pressure of arterial oxygen (PaO2) is below normal
Hypoxia - Insufficient oxygen
hypoxia - Increased O2 ... unable to use O2 ... O2 delivery to tissues ... diagnosis #comparison #pulmonary
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Left Shift (↓ O2 ... Right Shift (↑O2 ... pathophysiology #pulmonary
Medications for High-Altitude Sickness 
Acetazolarnide 
 • Carbonic Anydrase Inhibitor Bicarb diuresis & metabolic Acidosis ->
Anti-emetic O2 ... • Decreases pulmonary ... pressure Hyperbaric O2