31 results
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... ARB, diabetes) ACE ... potential Ca2+ channel ... failure Ca2+ channel ... contraindications #table
Hyperkalemia management algorithm 2023-2024 based on UKKA and KDIGO guidelines.

#hyperkalemia #electrolytes #algorithm #emergency #management

Notes:

(1) Up to
algorithm 2023- ... #algorithm #emergency ... have a normal ECG ... manifestations such as ... (4) Due to high
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... ECG changes, weakness ... changes? ... #Treatment #Algorithm
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Angiotensin-converting enzyme (ACE ... Heparin) • Sodium-channel ... • Increased EC ... MunerMohamed1 #hyperkalemia
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Diagnostic Approach to Hyperkalemia ... transplant - SLE High ... LMW heparin - ACE-I ... Beta-Blockers #Hyperkalemia ... #Algorithm #diagnosis
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... potassium and ECG ... changes • 5.5 ... #potassium #high
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... • Mechanism: Exchanges ... increase dose as ... patients sensitive to high ... #pharmacology #table
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
whose positive charges ... whose positive charges ... we introduce a high ... causes Hyperkalemia ... The high CL- content
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... • NSAIDs • ACE ... kiwis, mangoes, oranges ... causes #potassium #high
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; changes ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table