6 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Heparin) • Sodium-channel ... • Increased EC ... differential #diagnosis #pathophysiology ... pharmacology #potassium #medications
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... • Mechanism: Exchanges ... aspiration #Potassium #Binding ... medications #pharmacology ... #table #comparison
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
Typical ECG ... proportion to other findings ... of hyperkalemia ... • If on a Ca2+ channel ... diagnosis #management #pathophysiology
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... , changes on ECG ... Figure 3 is an algorithm ... , and Table 3 summarizes ... medications used
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... Treatments: • K-Binding ... Resins - Exchanges
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
-60y (hormonal changes ... survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... incidental CXR finding ... Self-limiting, chronic but stable