8 results
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
- Acquired Causes ... Paraneoplastic (e.g ... ), TEMPI (VEGF normal ... Matthew Ho, MD ... Diagnosis #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera ... JAK2 mutation OR Abnormally ... transformation into AML or MDS ... concentration in the normal ... #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
in mild cases) ... hemophilia type (e.g ... by a hemophilia treatment ... Avoid meds that ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... aplastic anemia Treatment ... Anemia #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... Syndromes #diagnosis #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... are usually near-normal ... PV, MDS, CML) Treatment ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Pyoderma Gangrenosum (PG)
50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
progressively worse s/p I&Ds ... medications in most cases ... corticosteroid (eg ... PG secondary treatment ... clinical #photo #dermatology