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diagnosis hematology causes hemolytic autoimmune extravascular intravascular neutropenia pancytopenia secondary thrombocytosis treatment warm
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... • Blood smear: Differential ... #management #treatment ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) - HELLP syndrome ... uremic syndrome ... Extravascular #Causes #differential ... #anemia
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... hemoglobinuria • Antibody-mediated ... hemolysis Nutritional ... #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... iron deficiency, hemolysis ... inflammatory disorders (e.g ... Myelodysplastic syndrome
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Neutropenia - Differential ... treatment - Maternal antibody ... Constitutional disorders, eg ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare
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