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diagnosis differential causes rheumatology hematology allergy hypersensitivity reactions workup acidosis allergic approach arthritis cryofibrinogenemia cryoglobulins definitions dementia dermatology disease elevation
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... hematological disorders ... to Autoimmune Disorders ... connective tissue disorder ... #classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type ... Days (Hemolytic Anemia ... Complex-Mediated ... Rash, SJS) - Amelia ... #Classification
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Differential Diagnosis Algorithm ... • Factitious disorder ... • Sickle Cell Anemia ... Thalessemia • Cryoglobulinemia ... Viral - Herpes simplex
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Classification ... Differential #Diagnosis #Algorithm
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Autoimmune Hemolytic anemia ... Antigen-Ab immune complexes ... #Classification
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
space) Immune-Complex ... lupus nephritis, cryoglobulinemia ... autoAb against type ... Glomerulonephritis #RPGN #Classification
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... categorized as a central type ... involves production disorders ... or a peripheral type ... that involves disorders
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... Chronic hemolytic anemia ... Hypertension #PHTN #Classification
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
precipitating complex ... Divided Into Two Types ... vasculitis, sepsis or cryoglobulinemia ... Associated Disorders ... Calciphylaxis • Cryoglobulinemia
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
neurocognitive disorders ... diagnostic workup What type ... - Progressive amnesia ... hallucinations - Movement disorders ... Differential #Subtypes #Classification
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