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diagnosis differential dermatology rheumatology allergic allergy cryofibrinogenemia cryoglobulinemia cryoglobulins gammopathy hearing hematology hypersensitivity hypertension loss lymphoproliferative management mgrs monoclonal oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... hematological disorders ... #classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity: Definitions ... cell surfaces causes ... antigen-surface complex ... antibody-antigen complexes ... #Classification
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... neurofibromatosis, vasculitis ... #Differential #Causes
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Differential Diagnosis Algorithm ... insufficiency • Vasculitis ... • Factitious disorder ... Viral - Herpes simplex ... #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Infection - Vasculitis ... - Collagen disorders ... Work Up: • Complete
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... (PTLD) Definition ... Diagnosis and classification ... to 50% of PTLD cases ... Lymphoproliferative #Disorders
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
Hearing Loss Types ... • Stroke • Vasculitis ... cause unknown) ... Mitochondrial disorders ... Streptococcus ○ Herpes simplex
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
precipitating complex ... Divided Into Two Types ... malignancies, vasculitis ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... or plasma cell disorder ... guide subtype classification ... formation causing vasculitis ... Types of MGRS-Associated
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