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diagnosis hematology hemophagocytic lymphohistiocytosis rheumatology activation cellulitis differential disorders hemeonc histiocytosis hodgkins idsa infections langerhans lch lymphoma lymphomas lymphoproliferative macrophage
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... , Hb), Hepatic dysfunction ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Responsive to Treatment ... growth, response to treatment ... Lymphoproliferative #Disorders #Classification ... #differential #algorithm
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
genetic immune dysfunction ... Low or absent NK cell ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... cytopenias and organ dysfunction ... Persistent fever, organ dysfunction ... search for and treatment ... Treatment Approach
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... -95% of cases) Classification ... Hodgkin Lymphoma Treatment ... lymphoma #diagnosis #classification ... hematology #oncology #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... IL-1 and IL-6, leading ... nervous system (CNS) dysfunction ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). Mild infection: for
IDSA Algorithm for ... the Management ... 12 000 or <400 cells ... oral antibiotic treatment ... evidence of organ dysfunction
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... • Endocrine Dysfunction ... TREATMENT OPTIONS ... with appropriate treatment ... Histiocytosis #Diagnosis #Management
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