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Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... Intrinsic Causes ... Intravascular Causes ... incompatibility • Paroxysmal ... #Hemolytic #Anemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... Transfusion reaction, Paroxysmal ... Extravascular #Causes ... diagnosis #hematology #anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... and petechiae Causes ... marrow-failure syndromes • Paroxysmal
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
irregular rhythms: Paroxysmal ... twitching CARDIAC CAUSES ... • Bradycardia caused ... NON-CARDIAC CAUSES ... Hyperthyroidism • Anemia
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... Donath-Landsteiner HA (paroxysmal ... Autoimmune #Hemolytic #Anemia
Peripheral and Central Causes of Vertigo Peripheral Causes (Common): - Labyrinth: Benign paroxysmal positional vertigo, Méniére disease,
Peripheral and Central Causes ... Vertigo Peripheral Causes ... Labyrinth: Benign paroxysmal ... oticus), Vestibular paroxysmia ... Central Causes
Causes of anemia in infants & children #Diagnosis #Peds #Pediatrics #Differential #Anemia #Causes #Algorithm
Causes of anemia ... #Differential #Anemia ... #Causes #Algorithm
Causes of Pediatric Spells - Differential Diagnosis Algorithm Neonates and Infant Spells: • Benign Sleep Myoclonus •
Causes of Pediatric ... spells • Benign Paroxysmal ... Vertigo • Benign Paroxysmal ... Diagnosis #Algorithm #Causes
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... iron deficiency anemia ... Autoimmune hemolytic anemia ... autoimmune hemolytic anemia ... , Paroxysmal cold
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... #Differential #Causes
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