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Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... elliptocytosis Extrinsic Causes ... Intravascular Causes ... incompatibility • Paroxysmal ... classification #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Transfusion reaction, Paroxysmal ... Extravascular #Causes ... differential #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... marrow-failure syndromes • Paroxysmal ... Anemia #oncology #hematology
Peripheral and Central Causes of Vertigo Peripheral Causes (Common): - Labyrinth: Benign paroxysmal positional vertigo, Méniére disease,
Peripheral and Central Causes ... Vertigo Peripheral Causes ... Labyrinth: Benign paroxysmal ... oticus), Vestibular paroxysmia ... Central Causes
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Infiltration: • Hematologic ... and non-hematologic ... Diagnosis #Algorithm #Causes ... #Hematology
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis #causes
Causes of Pediatric Spells - Differential Diagnosis Algorithm Neonates and Infant Spells: • Benign Sleep Myoclonus •
Causes of Pediatric ... spells • Benign Paroxysmal ... Vertigo • Benign Paroxysmal ... Diagnosis #Algorithm #Causes
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Nodosum #Mnemonic #Causes ... Differential #Diagnosis #Dermatology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Donath-Landsteiner HA (paroxysmal ... Diagnosis #Table #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Non malignant hematologic ... states • Non-hematologic ... Diagnosis #Algorithm #Causes ... #Hematology
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