14 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Relevant HES Variants ... disordersDiagnosis ... and Treatment Algorithm ... #Syndrome #HES ... #Hematology #eosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia ... Syndrome (HES) ... eosinophilia Secondary Causes ... #Syndrome #HES ... #hematology #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... for secondary causes ... eosinophilia (common causes ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • ... #Algorithm #Causes ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Non-lmmune #Anemia #Classification ... #Algorithm #Causes ... #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... for alternative causes ... Hepatic vascular disorder ... (e.g. ascites), ... #Algorithm #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Algorithm #Causes ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
hyperbilirubinemia syndrome ... • Has a UGT1A1 ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... (HUS) • Other ... lymphoproliferative disorders ... #hematology #anemia