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diagnosis oncology leukemia treatment cancer chronic classification common crisis cvid differential hemophagocytic hlh hodgkins hypogammaglobulinemia immunodeficiency immunology lymphocytic lymphohistiocytosis lymphoma
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Anemia • Toxic ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... #hematology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... aplasia • ITP ... ’s lymphoma or acute ... workup #oncology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... presents as an acute ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis (SRC) Clinical ... Renal Crisis: 1) Acute ... microangiopathic hemolytic anemia ... rule out other pathology ... Renal #Crisis #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... • Pain in LN ... classification #hematology ... #oncology #management
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... clonal evolution to acute ... disease tolerate anemia ... importance of clinical ... #algorithm #hematology
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