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diagnosis management apml chronic cll differentiation emergencies eosinophilia gap globulin hodgkins lymphocytic lymphoma mds myelodysplasia myelodysplastic neutrophilia oncologic protein proteingap
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... - Increased Neutrophils ... • Epinephrine Cancer ... #Increased #Neutrophils ... #Causes #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Causes: - Idiopathic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... : • Absolute neutrophil ... Hyperuricemia • Acute ... diagnosis #cancer
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- Differential ... - DRESS - AIN ... Mastocytosis - Acute ... Hypereosinophilic Syndrome ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
): • Neutrophils ... ): • Neutrophils ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... • Polyclonal increase ... microglobulin Treatment ... ’s lymphoma or acute ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... febrile neutrophilic ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(hypogranular neutrophils ... • Hairy Cell Leukemia ... blood count with differential ... #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hemolytic anemia • Pain ... ) Classification ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... an increase in ... #diagnosis #hematology
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