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differential rheumatology vasculitis algorithm clinical cryofibrinogenemia cryoglobulins lesions manifestations monoclonal oncology paraproteinemias semiology signs skin skinrash types ulcerative vasculitides
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Mycosis fungoides (cutaneous ... • Bleomycin Hematologic ... Thalessemia • Cryoglobulinemia ... ulcerative #skinrash #dermatology ... #Algorithm #causes
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... #Vasculitis #dermpath ... #dermatology #semiology ... signs #lesions #diagnosis ... manifestations #pathology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential Diagnosis ... nodules, Deep ulcers ... Urticarial/LCV) - Cryoglobulinemic ... Associated: - Microscopic ... Vasculitis #skin #dermatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Purpura - Skin ulcers ... vasculitis - GPA, EGPA, microscopic ... Henoch-Schönlein purpura) • Cutaneous ... #types #classification
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... et diutinum Neurologic ... Scleromyxedema (Dermato-neuro ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... tract, and often causes ... genital aphthous ulcers ... , cutaneous, ocular ... classification
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
sensitivity • Painful ulcers ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... (PR3-ANCA)): Microscopic ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
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