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differential rheumatology vasculitis algorithm oncology rash clinical cryofibrinogenemia cryoglobulins dermatologic gpa granulomatosis lesions manifestations monoclonal paraproteinemias petechiae petechial physicalexam polyangiitis
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... #Vasculitis #dermpath ... #dermatology #semiology ... signs #lesions #diagnosis ... manifestations #pathology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential Diagnosis ... Urticarial/LCV) - Cryoglobulinemic ... Associated: - Microscopic ... #dermatology #rheumatology ... #differential #diagnosis
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
insufficiency • Vasculitis ... Mycosis fungoides (cutaneous ... Thalessemia • Cryoglobulinemia ... ulcerative #skinrash #dermatology ... #Algorithm #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... - GPA, EGPA, microscopic ... Henoch-Schönlein purpura) • Cutaneous ... #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... tract, and often causes ... strong sign of cutaneous ... #rheumatology # ... classification
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Polyarteritis nodosa • Microscopic ... purpura • Mixed cryoglobulinemia ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... et diutinum Neurologic ... Scleromyxedema (Dermato-neuro ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... Sjogren's, GPA, EGPA, Microscopic ... #Algorithm #Causes ... #dermatology #physicalexam
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... (PR3-ANCA)): Microscopic ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... , sepsis or cryoglobulinemia ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... hematology
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