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differential aflp hellp obstetrics pregnancy thrombocytopenia ttphus antibodies associations autoantibodies cryofibrinogenemia cryoglobulins cutaneous defects dermatologic diseases gpa granulomatosis inherited monoclonal
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Urticarial/LCV) - Cryoglobulinemic ... Associated: - Microscopic ... Disease • Cogan syndrome ... #skin #dermatology ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... - GPA, EGPA, microscopic ... Cryoglobulins #diagnosis ... #types #classification ... #rheumatology #
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... granulomatosis - microscopic ... dermatomyositis #Size #Classification ... #Diagnosis #Rheumatology ... #Diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... /HSP • Cryoglobulinemia ... #hematology #rheumatology ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyarteritis nodosa • Microscopic ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... ANCA +MPO) • Cryoglobulinemic ... Dx: GPA, EGPA, microscopic ... #rheumatology # ... classification
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... Associations #diseases #diagnosis ... #table #rheumatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Biopsy: Typical pathologic ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Immunotactoid GN & Cryoglobulinemic ... Autoimmunity: • -MM/WM: Vasculitis ... (Cryoglobulinemic ... Paraproteinemias #Hematology ... #Differential #Diagnosis
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