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diagnosis antibodies classification antineutrophil associated cryoglobulins erythematosus laboratory rheumatic sle systemic testing types vasculitides workup
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
- C-ANCA pattern ... P-ANCA pattern ( ... >MPO Microscopic ... Anti-GBM disease ... #CANCA #PANCA #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... Microscopic polyangiitis ... - MPO>PR3 - ANCA ... >PR3 - ANCA+ 30- ... disease - MPO>PR3
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
myeloperoxidase (MPO-ANCA ... -ANCA): • Microscopic ... 100 % Commonly MPO-ANCA ... Vasculitis: + MPO-ANCA ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... : The ANA patterns ... Rheumatic Diseases ... • Rheumatic Diseases ... #patterns #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: ANCA Associated ... Pauci Immune (ANCA ... myeloperoxidase (MPO-ANCA ... -ANCA)): Microscopic ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... (e.g. systemic lupus ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... Serositis Labs: • ANA ... antibodies • (-) ANA ... Erythematosus #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... antibody (ANA) ... ACE level, CXR, ANCA ... #Disease #Rheumatoid
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