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differential classification antibodies antibody antineutrophil aortitis cryoglobulinemia disease nephrology patterns renal rheumatic size systemic types vessels workup
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Vasculitis: • ... Microscopic polyangiitis ... Renal-limited vasculitis ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... Vasculitis: + MPO-ANCA ... Dx: GPA, EGPA, microscopic ... , and SLE) • Urinalysis ... #rheumatology #
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pauci-Immune: - ANCA-positive ... polyangiitis, Microscopic ... polyangiitis) - ANCA-negative ... Rheumatoid arthritis ... testing: anti-ANCA
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... Nodosa (PAN), ANCA ... associated vasculitis ... erythematosus (SLE ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... Rheumatic Diseases ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
small vessels - ANCA-associated ... granulomatosis - microscopic ... - systemic lupus ... erythematosus ... #Rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... SLE), rheumatoid ... classification #rheumatology ... #vasculitis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
: • ANCA-associated ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
rheumatic diseases ... : ANCA Associated ... Pauci Immune (ANCA ... )): Microscopic ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... SLE) - Antinuclear ... ACE level, CXR, ANCA ... #testing #Rheumatology
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