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diagnosis classification differential antibodies ana antibody antineutrophil autoantibodies cryoglobulinemia cryoglobulins erythematosus pulmonary renal rheumatic size sle systemic table testing types
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Vasculitis: • ... Microscopic polyangiitis ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology ... #diseases
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Associations ANA ... c-ANCA - Vasculitis ... - Vasculitis, e.g ... Microscopic polyangiitis ... #table #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Vasculitis of ... small vessels - ANCA-associated ... granulomatosis - microscopic ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... Vasculitis: + MPO-ANCA ... diseases, such ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis (Eosinophilic ... polyangiitis, Microscopic ... vasculitis (IgA-associated ... vasculitis, Behcet ... testing: anti-ANCA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such ... atherosclerotic disease ... most important diseases ... )): Microscopic ... Differential #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... classification #rheumatology ... #vasculitis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... polarized light microscopy ... ACE level, CXR, ANCA ... #Disease #Rheumatoid
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