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differential algorithm causes injury acute albumin gradient pbc primary rheumatology transaminitis antibodies associations autoantibodies chemistry cholangitis dili diseases druginduced gap
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... < 1.1: Biliary ... #gradient #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Diagnosis Chronic ... liver disease ( ... hepatitis) - 80% ... Failure, Pancreatic, Biliary ... #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) ... - Alcoholic hepatitis ... - Massive liver ... Tuberculosis - Biliary ... #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
of Severe Acute Liver ... - Autoimmune ... disease - Hemochromatosis ... #Differential #Hepatology ... #Diagnosis
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Cirrhosis ... - Alcoholic hepatitis ... #Causes #diagnosis ... #differential #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Schistosomiasis - Autoimmune ... congenital - Primary biliary ... Nonalcoholic fatty liver ... 14 percent) #Diagnosis ... #Differential #Hepatology
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Autoimmune ... Cirrhosis #Hepatomegaly ... Algorithm #Causes #Hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... (SAAG>I.I), esophageal ... /acute hepatitis ... pregnancy • Primary biliary ... #causes #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Ischemia • Autoimmune ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Liver biopsy findings ... #Cirrhosis #Diagnosis ... #Algorithm #hepatology
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