14 results
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
RA: rheumatoid arthritis ... LungDisease #CTILD #Diagnosis ... #Differential # ... Comparison #Table ... #Pulmonary #Rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
with temporal arteritis ... viral load Drug-induced ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
e.g., congenital hip ... Enthesitis: • Site of pathology ... Joint #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... Effusions: - Hematologic ... #diagnosis #msk ... #physicalexam
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... - Alcohol-induced ... #oncology #diagnosis ... #differential # ... hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... fraction < 20% Differential ... Diaqnoses: • ... #management #treatment ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... spine, shoulders, hips ... Inflammatory • Crystal induced ... #Diagnosis #MSK ... #rheumatology #
Reactive or "Atypical" Lymphocytosis
Infection
 • Viral: EBV, CMV, HIV, Herpes viruses, Influenza, Varicella, HTLV-I
 • Bacterial:
Viral: EBV, CMV, HIV ... • Rheumatoid arthritis ... Hypersensitivity • Drug induced ... Lymphocytosis #differential ... #diagnosis #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... Constitutional symptoms, Arthritis ... druginduced #lupus #sle #comparison ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... extremities Drug Induced ... Antihistone: Drug induced ... Erythematosus #Diagnosis