25 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... Leukemia): • Lymphocytes ... -> Invade Skin: ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... cells can indicate disease ... leukemia #CLL ... workup #oncology #hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... Aggressive disease ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) ... • Most common leukemia ... immunophenotype Clinical ... chemotherapy for low-risk disease ... #hematology #hemeonc
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... I see all of these ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
common - T Cell ... ~10% - B-Cell ... Treated Like Acute Leukemias ... Classification #pathophysiology ... #Hematology #Diagnosis
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... trigger - Direct skin ... 50% of patients Skin ... infiltration (lymphocytes ... Urticaria #diagnosis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... involved) • No leukemic ... Noncontiguous spread • Clinical ... Lymphomas • Other hematologic ... #differential #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... syndrome • Giant cell ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Biopsy: Typical pathologic ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology