191 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... Howell-Jolly bodies #RBC ... #Hematology #Diagnosis
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology ... - Defects in RBC ... - Defects in RBC ... environment #Pathophysiology ... Hemolytic #Anemia #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Disorder • RBC ... Algorithm #Causes #Hematology
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholangitis #pathophysiology ... #pbc #psc #hepatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Macrocytes, Normal RBCs ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... ) - Abnormal RBCs ... Algorithm #Causes #Hematology
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC ... Contents #Volume #Hematology
Dysmorphic Red Blood Cells on Electron Microscopy
This eyeSCANdy image shows dysmorphic red blood cells from the
#Dysmorphic #RBCs ... SEM #clinical #pathology ... #hematology #nephrology
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Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... Smear ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... shape, HbS induces RBC ... This leads to RBC ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... relative with PBC ... Pathophysiology ... Cholestasis #PBC ... #hepatology