114 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... on Smear • Chronic ... Spherocytes on Smear ... #Algorithm #Causes
Plasmodium - Identification Algorithm
 • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
Identification Algorithm ... rings, <1/3 size RBC ... Multiple rings/RBC ... Identification #Algorithm ... #pathology #smear
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... Howell-Jolly bodies #RBC ... #Hematology #Diagnosis
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential Diagnosis ... Algorithm Signs ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
expression of Kell RBC ... McLeod #Syndrome #Smear ... #Pathology #Microscopy
Red Blood Cell Morphology Atlas

Size variation, Hemoglobin distribution,  
Hypochromia,  
Shape variation,  
Inclusions, 
Red
distribution #Diagnosis ... #Path #Blood #Smear ... #RBC #Morphology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... 2) External (RBC ... 3) Internal (RBC ... Peripheral Blood Smear ... #Differential #Diagnosis
Plasmodium vivax on peripheral smear
A college student presents w/ headache, fever, chills. Returned 2 days ago
on peripheral smear ... Diagnosis? ... Diagnostic morphologic ... enlarged infected rbc ... blood #clinical #pathology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management Algorithm ... Initial labs: CBC ... Reticulocytes, smear ... MAHA likely: • Smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Algorithm Normal ... Blood Smear • ... Neutrophils - Low RBC ... #Algorithm #Causes