15 results
diagnosis oncology anemia chronic causes cll differential leukemia lymphocytic syndrome aplastic apml approach autoimmune bacilliformis bartonella bloodsmear borrelia clinical coagulation
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Decreased RBC ... Thalassemia • RBC ... Disorder • RBC ... Non-lmmune #Anemia #Classification ... #Causes #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... ↑ LDH • Anti-RBC ... C3d • Blood smear ... Anemia #diagnosis #management ... #treatment #rheumatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... Initial labs: CBC ... Reticulocytes, smear ... #Algorithm #hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... anorexia, ARDS ​• RBC ... phase: Peripheral smear ... TREATMENT: ​• Acute ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Triggers: Diuretics, PRBC ... - 80% have fever ... • Lab values: WBC ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
if high risk if WBC ... Subacute-Acute: • Common: fever ... QD until normal WBC ... APML #diagnosis #management ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... Vmphocytosis on routine CBC ... ) B symptoms → fevers ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Peripheral Blood Smear ... Hgb 12.5, WBC 14 ... Treatment is tetracycline ... initiation of treatment ... BloodSmear #microscopy #pathology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... incidentally via CBC ... • Treatment algorithms ... PV #Diagnosis #Management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
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