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differential leukemia causes cll anemia classification coagulation diffuse disseminated hemeonc hemolytic hodgkins intravascular lad lymphadenopathy lymphoma mds myelodysplasia myelodysplastic plasmacytoma
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Algorithm Reactive ... Age > 50 • Chronic ... (CBC with Lymphocytes ... Reed-Sternberg Cells ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Peripheral smear ... #Chronic #Lymphocytic ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... • Peripheral smear ... #Chronic #Lymphocytic ... #Leukemia #oncology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Fibrinolysis & DIC ... (Chronic Lymphocytic ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... cells - Consider ... thrombocytopenia - DIC ... #Algorithm #workup ... #hematology #testing
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Peripheral smear ... Schistocytes, helmet cells ... hydration • RBC ... #Coagulation #diagnosis ... #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... Better call hematology ... normal/high - Chronic ... #Algorithm #workup ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... Marrow Failure • Chronic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... platelets - WBC ... lymph node biopsy (diagnostic ... classification #hematology ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• CBC + diff • ... IFE, FLC assay Pathology ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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