12 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... smear - RBC agglutination ... Mycoplasma, EBV, HIV ... sensitize red blood ... hemolytic #anemia #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... and laboratory diagnosis ... #Pathology #Smear ... #Microscopy
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
occurs when the plasma ... #Clinical #Pathology ... #Blood #Smear # ... Microscopy #Rouleaux ... #Formation #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... : • + Clinical ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... Sjogren's, GPA, EGPA, Microscopic ... ITP - APLS - HIT ... #dermatology #physicalexam
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
LBRF can be diagnosed ... with a blood smear ... can be used for diagnosis ... recurrentis #BloodSmear #microscopy ... #pathology #clinical
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... • Anemia • Aplastic ... smear • Bone marrow ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Peripheral smear ... #Coagulation #diagnosis ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Anemia Clinical ... and petechiae Causes ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
illness, high plasma ... of high parity blood ... without other cause ... Transfusion #Reactions #hematology ... #diagnosis #comparison