132 results
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... hemorrhagic rash; symptoms ... lymph -> Koplik's spots ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... • Other rare causes ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Pathogenesis and Clinical ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Achilles Tendon Rupture in Slow Motion

Caused by high speed knee extension with ankle dorsiflexion.

Dr. Boris Gojanovic
Slow Motion Caused ... Rupture #SlowMotion #clinical ... #Video #Sports ... #Mechanism #PhysicalExam
Measles (Rubeola) 
Clinical 
 • High fever 
 • Cough, Coryza, Conjunctivitis (The 3 C's)
Measles (Rubeola) Clinical ... C's) • Koplik spots ... Pneumonia (most common cause ... KoplikSpots #Features #Symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... deficiency: - Short ... #FeedbackLoop #endocrinology ... #pathophysiology
Clinical Features of Infective Endocarditis

General 
 - Malaise 
 - Clubbing 

Cardiac 
 - Murmurs
Clinical Features ... Eyes - Roth spots ... #Endocarditis #Symptoms ... Signs #Features #PhysicalExam
Rachitic Rosary of Rickets on Physical Exam

Bead-like prominences of bone are seen at the costochondral joints.
mineralization causes ... Rosary #Rickets #PhysicalExam ... #clinical #video ... VitaminD #deficiency #endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... diabetes Key signs/symptoms ... hypotension) DKA: Short
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Pathogenesis and Clinical ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology