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diagnosis management differential syndrome treatment hiv infections inflammatory iris opportunistic reconstitution barre cns cytomegalovirus guillain guillainbarre hemophagocytic hivaids hlh infectiousdiseases
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
) in HIV-AIDS Patients ... patient with HIV and CD4 ... 50 or less: • Neurologic ... Retinitis (Most common cause ... of blindness in AIDS
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology Risk factors: - Low CD4 count - Disseminated OI -
Syndrome (IRIS) - Pathophysiology ... factors: - Low CD4 ... response to OI (in CM ... Syndrome #IRIS #Pathophysiology ... #AIDS
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... +: Virus (EBV, CMV ... or biologics (CMV
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Infection in HIV / AIDS ... required until immune ... Demyelinating disease caused ... - Generally >3 cm ... differential #diagnosis #AIDS
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... jejuni - HIV, CMV ... management #treatment #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... treatment of HIV/AIDS ... be present: • AIDS ... keratitis, iritis • CMV ... unintentional weight loss, nausea
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... activation of an immune ... • Infectious causes ... , HIV, Hep A/B/CMV ... diagnosis #management #neurology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS Preventing Chronic Microsporidiosis: • Because chronic microsporidiosis occurs
IDSA Recommendations ... Microsporidiosis in HIV-AIDS ... optimize ART with immune ... Gastrointestinal Infections Caused ... Microsporidiosis #IDSA
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