15 results
diagnosis management monoclonal oncology treatment gammopathy chronic cll dermatomyositis differential hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis multiplemyeloma summary agglutinin algorithm anemia
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS) Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... ) Mayo Clinic Risk ... CBC, complete blood ... monoclonal #gammopathy #MGUS ... diagnosis #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... Ig deposition disease ... Monoclonal #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... Cr >2 mg/dL or CC ... chain deposition disease ... #Gammopathies #MGUS ... #diagnosis #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... auricular papules Clinical ... severity of the disease ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... not feasible CMC ... Diagnosis #Management #dermatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... vaccinations Renal disease ... Ig deposition disease ... rituximab (in clinical ... Complications #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Disease ... Cold Agglutinin Disease ... Viral Infection Clinical ... significance (MGUS ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Lymphocytosis on CBC ... cells can indicate disease ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... treatment #summary #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
incidentally via CBC ... present, symptoms, signs ... von Willebrand disease ... Summary #treatment #hematology
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