6 results
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
either made in the liver ... or not by the liver ... source: Malignancy, Infection ... liverprof #Diagnosis #Hepatology ... Interpretation #Differential
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Acute fatty liver ... < 1.1 g/dL) Infections ... Causes #diagnosis #differential ... #hepatology #SAAG
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... +++ (Plt, Hb), Hepatic ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... or higher • Liver ... bile ducts Differential ... malignancies, Hepatic ... fungal, viral infections
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... hypotension or septic ... #Bandemia #differential ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Triggers: ▪ Infections ... - Elevated liver ... Pathophysiology ... of NK cells and CD8 ... #Hematology #HemeOnc