17 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Diagnosis: • ... Lymphocytosis on CBC ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Auto-amplification loop Diagnosis ... lymphoma, B-cell ... #management #treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
(CDI) - Diagnosis ... and Management ... Perforation) Pathophysiology ... - produced by all ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... Complications: 1) Infection ... Lymphocytic #Leukemia #oncology ... #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... procedures - Infection ... decreased PLT count: CBC ... not required in all
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... Diagnosis: • ... #Bandemia #differential ... #WBC #CBC #hematology ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... Diagnosis: Infection ... #management #hematology ... #oncology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... pancreatic islet cell ... Differential Diagnosis ... and Workup: • ... #Management #Endocrinology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... polymicrobial infection ... Lung Abscess Pathophysiology ... : • CBC - Leukocytosis ... Lung Abscess Differential
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
with differential ... workup or TSH level ... if symptoms of infection ... Pyridostigmine - New diagnosis ... MyastheniaGravis #Checklist #Management