88 results
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... Rare causes: ... CD3-CD4+ T cells ... malignancy - Immune deficiency ... hypereosinophilia #HE #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential ... Artifact (redo CBC ... disorders • Celiac disease ... effect following treatment ... malignancy • Iron deficiency
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Edema, Celiac disease ... #differential # ... diagnosis #causes
Vitamin deficiency causes clinical disease
Vitamin C deficiency causes scurvy.  Vitamin C is important for the
Vitamin deficiency ... causes clinical ... disease Vitamin ... C deficiency causes ... #Pathophysiology
Causes of Hypermagnesemia
Increased magnesium load
 - Magnesium-containing laxatives, antacids, or enemas
 - Treatment of pre-edampsia/eclampsia (mothers
Causes of Hypermagnesemia ... or enemas - Treatment ... Mineralocorticoid deficiency ... insufficiency (Addison's disease ... #diagnosis #differential
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... endpoint of all-cause
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
this interesting case ... Diagnosis was made by radiology ... testing and expedite treatment ... leukodystrophy w/ deficiency ... #Radiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Cellular immune deficiency ... Drugs, Unknown cause ... Treatment: •
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical ... due to chronic disease ... hyperparathyroidism Treatment ... Syndrome #Nutrition #Differential ... #Diagnosis #Pathophysiology
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Heart Failure - Pathophysiology ... and Differential ... #Differential # ... Diagnosis #cardiology ... #causes