21 results
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Ill-appearing, vital sign ... New-onset fever with rash ... #Diagnosis #Dermatology ... #Rash #Maculopapular ... Targetoid #Algorithm #Differential
Quincke’s sign from arterial dilation in a dermatitic rash

#Quinckes #sign #aortic #regurgitation #clinical #video #cardiology #dermatology
Quincke’s sign from ... in a dermatitic rash ... regurgitation #clinical ... #video #cardiology ... #dermatology #rash
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... #dermatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... The signs and symptoms ... ▪ “Rash” (75% ... #Diagnosis #Clinical ... #Photo #Dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic Symptoms ... extensive skin rash ... Symptoms: • The ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
and symptoms helps ... differentiate it ... Dermatomyositis #Rash ... Dermatomyositis #Dermatology ... #Clinical #Photo
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Maternal Support - Critical ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology