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diagnosis leukemia management oncology symptoms workup anorexianervosa arterial biliary bulimianervosa cholangitis chronic cirrhosis cll differential embolism hemeonc hemophagocytic hlh leukostasis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Testosterone - Coumadin skin ... • Nephrotic Syndrome ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... Examination: • Skin ... diagnosis #workup #hepatology
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
and memory loss HEMATOLOGIC ... (yellowing of skin ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Tumor lysis syndrome ... CLL -> Invade Skin ... Transformation: • Complication ... #Leukemia #Hematology
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... hormone levels cause ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... caused by uncontrolled ... Presentation • Common Signs ... Pathophysiology ... Diagnosis #Management #Hematology
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