158 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis ... #causes
Yao Syndrome vs VEXAS

Zhuoer Xie, MD @ZhuoerXie

#Yao #Syndrome #VEXAS #diagnosis #comparison #rheumatology
Yao Syndrome vs ... ZhuoerXie #Yao #Syndrome ... #VEXAS #diagnosis ... #comparison #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... and Primary Causes ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... Table #Pulmonary #Rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... Scleroderma) Multi-system ... LcSSc) - distal skin ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... anti-Sc170): Diffuse skin ... BCM_InternalMed #Systemic ... Autoantibodies #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology #
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory disease Skin ... Neuro disease: • Systemic ... Behcets #disease #Syndrome ... #pharmacology #rheumatology