38 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #LeserTrelat #Sign ... PhysicalExam #clinical #video ... #skin #dermatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... Staphylococcal scalded skin ... #TEN #Dermatology ... #PhysicalExam #Video ... Clinical #SJS #skin
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... - Pathophysiology ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Diagnosis #Dermatology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... diabetes Key signs ... hypovolemia (dry MM, skin ... hypotension) DKA: Short
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm

Face
 • Melasma
Abdomen
 • Linea Nigra 
Hormone induced
Physiologic Skin ... number (probable) Skin ... Campbell de Morgan spot ... • Chadwick's sign ... #dermatology #Differential
Kussmaul's Sign and Friedreich's Sign on Neck Examination

A middle-aged M with unknown PMH presents with dyspnea.
Kussmaul's Sign ... demonstrated in the video ... small blue-colored spot ... on the skin (middle ... PhysicalExam #Clinical #Video
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
are inflamed In skin ... Psoriatic plaques on skin ... , ridging, oil spots ... PsoriaticArthritis #pathophysiology ... #diagnosis #signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... deficiency: - Short ... tunnel, OSA, Incr skin ... endocrinology #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... erosions in ~20% Management ... #dermatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... arterial thrombosis, skin ... ♀, ↑Age, ESRD Pathophysiology ... exposure (prevent skin ... #Treatment #Hematology