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diagnosis syndrome differentiation leukostasis lysis oncology reactions table taco tls trali transfusion tumor
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... sepsis), PE, DAH, CHF ... #diagnosis #management ... #hematology #oncology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... : Age>60, CKD, CHF ... fluid balance, and CXR ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
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