11 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Primary Biliary Cirrhosis ... Primary Sclerosing Cholangitis ... #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... /Liver failure ... PBC Signs and Symptoms ... obstruction • ALP ... diagnosis #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
disturbance (obstructed liver ... Highest • Bone • Liver ... Most common symptoms ... Primary biliary Cholangitis ... Diagnosis #Algorithm #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
Primary Sclerosing Cholangitis ... • CHOLANGITIS ... • CIRRHOSIS - ... Care focuses on symptom ... management #summary #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... ) Pathophysiology ... postpartum): • Initial symptoms ... Pregnancy #hepatology ... diagnosis #management #pathophysiology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... Diagnosis Algorithm Symptoms ... Elevated ALP 2. ... Liver biopsy findings ... Diagnosis #Algorithm #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
suspected HH based on symptoms ... Step 3: All patients ... Patients with cirrhosis ... ALT, alanine aminotransferase ... diagnosis #management #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... synthesized in: liver ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Hyophosphatasia #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- B symptoms ... the spleen or liver ... translocation • Types: Classification ... Malignancies (eg CML, ALL ... #differential #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
lymphocyte predominant (LP ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis